Aussie Health and Info
DON'T BUY AN AUSSIE
Written by Lisa Giroux of K9station.com
You've done your homework. You took the online 'tests' to match your personality and lifestyle to a breed. You've read all you can find, and called every breed organization, breeder and owner you can unearth. You have had confirmed your suspicion that the Australian Shepherd is as near a perfect dog as the Great Spirit and man could have created. Of course, we devotees feel that way, but before it is too late, there is another side to the 'perfect' breed. This side is seldom presented in glossy ads or breeder packets, but needs to be said anyhow...before it is too late.
DON'T BUY AN AUSSIE FOR ITS LOOKS
Striking and unusual colors and markings are usually what attracts the average person to the Aussie. Looks, however, are only a small part of living with an Aussie. The true beauty of the Australian Shepherd shines outward from his character. An Aussie can be a strong guardian of your home and a dog that is not overtly social with people outside of your immediate family...is this something you will enjoy for the 14+ years of an Aussie's life? Buy an Aussie because you have researched the breed's temperament and personality, and think it is something that you could enjoy living with for a long time.......Read More.....
Article by Washington State University
College of Veterinary Medicine
Veterinary Clinical Pharmacology Lab
Many different drugs and drug classes have been reported to cause problems in dogs with the MDR1 mutation. The VCPL continues to work to identify
drugs that may be dangerous to dogs with the MDR1 mutation and to determine alternative drugs and doses for these dogs.
Drugs that have been documented to cause problems in dogs with the MDR1 mutation include:
- Ivermectin (antiparasitic agent) - While the dose of ivermectin used to prevent heartworm infection is SAFE in dogs with the mutation (6 micrograms per kilogram), higher doses, such as those used for treating mange (300-600 micrograms per kilogram) will cause neurological toxicity in dogs that are homozygous for the MDR1 mutation (MDR1 mutant/mutant) and can cause toxicity in dogs that are heterozygous for the mutation (MDR1 mutant/normal).
- Selamectin, milbemycin, and moxidectin (antaparasitic agents)- Similar to ivermectin, these drugs are safe in dogs with the mutation if used for heartworm prevention at the manufacturer's recommended dose. Higher doses (generally 10-20 times higher than the heartworm prevention dose) have been documented to cause neurological toxicity in dogs with the MDR1 mutation.
- Loperamide (ImodiumTM; antidiarrheal agent)- At doses used to treat diarrhea, this drug will cause neurological toxicity in dogs with the MDR1 mutation. This drug should be avoided in all dogs with the MDR1 mutation.
- Acepromazine (tranquilizer and pre-anesthetic agent)- Based on collaborative research, the VCPL has determined that dose reductions are required for dogs MDR1 mutant/mutant and MDR1 mutant/normal.
- Butorphanol (analgesic and pre-anesthetic agent)- Dose reduction required for dogs MDR1 mutant/mutant and MDR1 mutant/normal.
- Chemotherapy Agents (Vincristine, Vinblastine, Doxorubicin, Paclitaxel)- Based on collaborative research, the VCPL has determined that dose reductions are required for dogs MDR1 mutant/mutant and MDR1 mutant/normal in order to avoid SEVERE toxicity.
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